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1

ChemInform Abstract: Synthesis and Biological Evaluation of Substituted 4-(OBz)Phenylalanine Derivatives as Novel N-Type Calcium Channel Blockers.

Lain-Yen Hu, Todd R. Ryder, Sham S. Nikam, Elizabeth Millerman, Balazs G. Szoke, Michael F. Rafferty

Journal:

Year:

1999

File:

PDF, 32 KB

1999

2

ChemInform Abstract: A Simple Strategy for the Preparation of 6-Substituted 3H-Benzoxazol-2-ones and 3H-Benzothiazol-2-ones

Russell J. DeOrazio, Jun-Ho Maeng, David D. Manning, Brian A. Sherer, Ian L. Scott, Sham S. Nikam

Journal:

Year:

2012

File:

PDF, 30 KB

2012

3

AMPA Receptor Antagonists

Nikam, Sham, Kornberg, Brian

Journal:

Current Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 185 KB

english, 2001

4

Subtype Selective NMDA Receptor Antagonists: Evaluation of Some Novel Alkynyl Analogues.

Brian E. Kornberg, Sham S. Nikam, Jon L. Wright, Suzanne R. Kesten, Leonard T. Meltzer, Linda Coughenour, Bridget Barr, Kevin A. Serpa, Julie McCormick

Journal:

Year:

2004

File:

PDF, 81 KB

2004

5

Metabolism-Dependent Mutagenicity of a Compound Containing a Piperazinyl Indazole Motif: Role of a Novel P450-Mediated Metabolic Reaction Involving a Putative Oxaziridine Intermediate †

Chen, Hao, Murray, Joel, Kornberg, Brian, Dethloff, Lloyd, Rock, David, Nikam, Sham, Mutlib, Abdul E.

Journal:

Chemical Research in Toxicology

Year:

2006

Language:

english

File:

PDF, 335 KB

english, 2006

6

NR2B Selective NMDA Receptor Antagonists

Nikam, Sham, Meltzer, Leonard

Journal:

Current Pharmaceutical Design

Year:

2002

Language:

english

File:

PDF, 93 KB

english, 2002

7

Synthesis of hydroxamic acids: PdBaSO4 as a new catalyst for the deprotection of O-benzyl hydroxamates

Sham S Nikam, Brian E Komberg, Donald R Johnson, Annette M Doherty

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 190 KB

english, 1995

8

Regioselective synthesis of trimethylsilyl-substituted .alpha.-allenic alcohols via propargylic organoboranes

Wang, Kung K., Nikam, Sham S., Ho, Chihmei D.

Journal:

Journal of Organic Chemistry

Year:

1983

Language:

english

File:

PDF, 313 KB

english, 1983

9

Synthesis of trimethylsilyl-substituted .alpha.-allenic and .beta.-acetylenic amines from imines and propargylic and allenic organoboranes

Nikam, Sham S., Wang, Kung K.

Journal:

Journal of Organic Chemistry

Year:

1985

Language:

english

File:

PDF, 465 KB

english, 1985

10

Novel quenchers for solution phase parallel synthesis

Sham S. Nikam, Brian E. Kornberg, Stephanie E. Ault-Justus, Michael F. Rafferty

Journal:

Tetrahedron Letters

Year:

1998

Language:

english

File:

PDF, 189 KB

english, 1998

11

Serotonergic properties of spiroxatrine enantiomers

Nikam, Sham S., Martin, Arnold R., Nelson, David L.

Journal:

Journal of Medicinal Chemistry

Year:

1988

Language:

english

File:

PDF, 549 KB

english, 1988

12

The cyclization of trimethylsilyl-substituted .alpha.-allenic alcohols to 3-(trimethylsilyl)-2,5-dihydrofurans and their facile autoxidation to 3-(trimethylsilyl)furans or 4-(trimethylsilyl)-2(5H)-furanones

Nikam, Sham S., Chu, Kai Hsuan, Wang, Kung K.

Journal:

Journal of Organic Chemistry

Year:

1986

Language:

english

File:

PDF, 412 KB

english, 1986

13

Synthesis and biological evaluation of substituted 4-(OBz)phenylalanine derivatives as novel N-type calcium channel blockers

Lain-Yen Hu, Todd R. Ryder, Sham S. Nikam, Elizabeth Millerman, Balazs G. Szoke, Michael F. Rafferty

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 265 KB

english, 1999

14

Design and Synthesis of Novel Quinoxaline-2,3-dione AMPA/GlyN Receptor Antagonists: Amino Acid Derivatives

Nikam, Sham S., Cordon, John J., Ortwine, Daniel F., Heimbach, Tycho H., Blackburn, Anthony C., Vartanian, Mark G., Nelson, Carrie B., Schwarz, Roy D., Boxer, Peter A., Rafferty, Michael F.

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 99 KB

english, 1999

15

AMPA receptor agonists, antagonists and modulators: their potential for clinical utility

Bigge, Christopher F, Nikam, Sham S

Journal:

Expert Opinion on Therapeutic Patents

Year:

1997

Language:

english

File:

PDF, 260 KB

english, 1997

16

ChemInform Abstract: Synthesis of Novel Quinoxaline-5-carboxylic Acid Derivatives.

Brian E. Kornberg, Sham S. Nikam, Michael F. Rafferty

Journal:

Year:

2000

File:

PDF, 33 KB

2000

17

Subtype selective NMDA receptor antagonists: evaluation of some novel alkynyl analogues

Brian E. Kornberg, Sham S. Nikam, Jon L. Wright, Suzanne R. Kesten, Leonard T. Meltzer, Linda Coughenour, Bridget Barr, Kevin A. Serpa, Julie McCormick

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 174 KB

english, 2004

18

1-Aminoindanes as novel motif with potential atypical antipsychotic properties

James M. Graham, Linda L. Coughenour, Bridget M. Barr, David L. Rock, Sham S. Nikam

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 130 KB

english, 2008

19

Novel Selective Quinazoline Inhibitors of Endothelin Converting Enzyme-1

Kyunghye Ahn, Andre M. Sisneros, Sarah B. Herman, Sharon M. Pan, Donald Hupe, Chitase Lee, Sham Nikam, Xue-Min Cheng, Annette M. Doherty, Richard L. Schroeder, Stephen J. Haleen, Semiko Kaw, Noriaki E

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 160 KB

english, 1998

20

Novel Use of Substituted 1,4-Dihydrobenz[ d ][1,3]oxazin-2-ones in the Synthesis of Important Aminomethyl o -Nitroanilines

Nikam, Sham S., Yuen, Po-Wai, Kornberg, Brian E., Tobias, Brian, Rafferty, Michael F.

Journal:

Journal of Organic Chemistry

Year:

1997

Language:

english

File:

PDF, 163 KB

english, 1997

21

Phosphodiesterase 4 inhibition reduces lung fibrosis following targeted type II alveolar epithelial cell injury

Sisson, Thomas H., Christensen, Paul J., Muraki, Yo, Dils, Anthony J., Chibucos, Lauren, Subbotina, Natalya, Tohyama, Kimio, Horowitz, Jeffrey C., Matsuo, Takanori, Bailie, Marc, Nikam, Sham, Hazama,

Journal:

Physiological Reports

Year:

2018

Language:

english

File:

PDF, 647 KB

english, 2018

22

Synthesis of novel quinoxaline-5-carboxylic acid derivatives

Brian E. Kornberg, Sham S. Nikam, Michael F. Rafferty

Journal:

Journal of Heterocyclic Chemistry

Year:

1999

File:

PDF, 510 KB

1999

23

New Synthesis of Substituted Benzylamines. Novel Application of the Mitsunobu Reaction To Convert Substituted Benzyl Alcohols to Amines †

Nikam, Sham S., Kornberg, Brian E., Rafferty, Michael F.

Journal:

Journal of Organic Chemistry

Year:

1997

Language:

english

File:

PDF, 155 KB

english, 1997

24

3-Arylimino-2-indolones Are Potent and Selective Galanin GAL3 Receptor Antagonists

Konkel, Michael J., Lagu, Bharat, Boteju, Lakmal W., Jimenez, Hermogenes, Noble, Stewart, Walker, Mary W., Chandrasena, Gamini, Blackburn, Thomas P., Nikam, Sham S., Wright, Jon L.

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 30 KB

english, 2006

25

A Simple Strategy for the Preparation of 6-Substituted 3 H -Benzoxazol-2-ones and 3 H -Benzothiazol-2-ones

DeOrazio, Russell J., Maeng, Jun-Ho, Manning, David D., Sherer, Brian A., Scott, Ian L., Nikam, Sham S.

Journal:

Synthetic Communications

Year:

2011

Language:

english

File:

PDF, 153 KB

english, 2011

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